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Innovative Research of America(IRA) 是一家致力研发于药物定量定时缓释系统的专业化公司,又称Matrix-Driven Delivery (MDD) 给药系统。该给药系统由一个可生物吸收的基质组成,含有定量可控的活性给药成分,可以以设定的剂量在一定时间范围内进行给药。

 

Since it is not easy to administer drugs and hormones orally to research animals, several delivery methods have been devised as alternatives.  However, most scientists continue to labor with unreliable injectables to conduct their research.

 

Matrix-Driven Delivery (MDD) Pellet(MDD片剂)的优势

Saves time

Ready-to-implant

Insures controlled product release over time

Avoids "peak and valley" effects

Guarantees consistent product preparation

Extends product life against spontaneous breakdown

Extends product life against host-related breakdown

Minimizes experimental variables

Insures safety of the experimenter

Reduces neurophysiological trauma to animal/no excessive handling

Generates more meaningful and reproducible results

Superior to conventional delivery methods

Enhances experimental efficiency

Frees valuable time for creative research

Saves money

 

Innovative Research of America的主要产品包括:

ANTIBIOTICS

ANTI-INFLAMMATORY AGENTS

ANTI-NEOPLASTICS

CATECHOLAMINES & RELATED PRODUCTS

CORTICOIDS & DIURETICS

ESTROGENS & ANTI-ESTROGENS

FATTY ACIDS

MISCELLANEOUS PRODUCTS

NUCLEOTIDE RELATED PRODUCTS

PLACEBO

PROGESTINS

PROSTAGLANDINS

THYROIDS

VITAMINS

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Toronto Research Chemicals.jpg

Toronto Research Chemical建立于1982年,致力于为生物医药研发人员提供小分子有机物,库存超过57000种,并通过一系列方法保证标准物质的纯度。

 

Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.

 

Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.

 

Toronto Research Chemical的产品涵盖:

Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.

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Life Diagnostics.png

Life Diagnostics公司专注于研发和生产临床前研究以及动物医学诊断相关的ELISA试剂盒、纯化的生物标志物和抗体等产品。产品覆盖心血管疾病、急性期反应、免疫毒性和免疫学标志物等研究领域,主要应用于小鼠、大鼠、兔、猫、狗、猪、猴和鸡等物种。此外,鉴于越来越多的研究围绕聚乙二醇化(PEGylated)生物制剂,Life Diagnostics公司也开发出了抗体PEG单克隆抗体和ELISA试剂盒用于检测PEG以及PEG化的蛋白。

 

Life Diagnostics manufactures ELISA kits, SPARCL™ kits, purified biomarkers and antibodies for preclinical research and veterinary diagnostics. Our areas of expertise include cardiovascular, acute phase, immunotoxicity and immunology biomarkers in species including mouse, rat, rabbit, cat, dog, pig, cow, monkey and chicken. Because of the increasing research into PEGylated biologics we have also developed anti-PEG monoclonal antibodies and ELISA kits for detection of PEG, mPEGylated proteins and anti-PEG antibodies. We manufacture all of the products listed on our website.

 

Life Diagnotics目前可提供用于检测骨骼肌肌钙蛋白-I(troponin-I)、肌红蛋白(myoglobin)、脂肪酸结合蛋白(fatty acid binding protein, FABP)以及肌球蛋白轻链(myosin light chain-1, MLC-1)等代表性标志分子的ELISA试剂盒;主要提供针对检测小鼠、大鼠、兔、狗、猪和猴等种属的检测试剂盒。与肌红蛋白蛋白和心脏型FABP不同,骨骼肌肌钙蛋白I特异性表达于骨骼肌细胞,因此为检测肌肉损伤的首选标志物分子。

 

Life Diagnotics生产的PEG试剂主要包括抗体、ELISA试剂盒以及PE化蛋白。

(1)PEG抗体

(2)PEG ELISA试剂盒:竞争法ELISA检测PEG化蛋白(含甲氧基,或不含甲氧基);夹心法ELISA快速检测甲氧基PEG(mPEG)和mPEG化蛋白;抗PEG IgG和IgM ELISA试剂盒用于检测小鼠、大鼠和猴血清或血浆中PEG抗体的水平。

(3)PEG化蛋白

 

此外,Life Diagnostics还提供PEG包被的微孔板和封闭缓冲液,专门设计用于免疫检测PEG或PEG化抗体。大多数商业化的ELISA试剂盒含有去垢剂如Tween-20(一种含有PEG的去垢剂)会干扰PEG的检测。Life Diagnostics公司提供的封闭缓冲液不含去垢剂和PEG, 可用于稳定包被有PEG或PEG抗体的平板。

 

Life Diagnostics除提供多种心肌标志物ELISA检测试剂盒之外,还生产多种纯化的心肌生物标志物蛋白,包括肌钙蛋白I、肌钙蛋白T、肌钙蛋白复合物、肌红蛋白和脂肪酸结合蛋白等,可提供来自不同物种包括人、小鼠、大鼠、豚鼠、兔、狗、猪、牛和猴的蛋白。

 

主要产品包括:

SPARCL Kits

Acute Phase Rgts. »

Cardiac Biomarkers »

Immunoglobulin Rgts. »

Immunotoxicity ELISA Kits

PEG Reagents »

Skeletal Muscle Rgts. »

Liver Biomarkers

Misc Biomarkers

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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