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艾美捷科技特约代理Chiralix公司产品。

Chiralix是一家专业从事手性有机分子合成和供应的公司,致力于制药公司及生命科学研究领域的实验室研究用特有手性分子的生产和研发。Chiralix集先进的有机分子合成、过渡金属催化、生物催化技术于一身,具备灵活与高效的多种手性分子合成工艺,如基团的氨基酸,叠氮酸,氨基醇及多种肽段模块。除了提供大量的手性分子成品,还提供优质的研发服务,如复杂有机分子的合成等。

 

Chiralix is a specialist in chiral organic synthesis. We offer a unique range of chiral drug-like building blocks on research-scale, aimed at research laboratories in pharmaceutical companies and all others involved in the Life Sciences industry. The integration of our capabilities in the areas of advanced organic synthesis, transition metal catalysis and biocatalysis, enables us to develop flexible and efficient synthetic routes to diversely substituted chiral molecules, such as specialty amino acids, azido acids, amino alcohols and peptide building blocks. In addition to our catalog of unique building blocks, we provide high quality contract research services for our clients in support of their own research efforts. Our services include the custom synthesis of complex organic molecules and the parallel synthesis of compound libraries.

 

Chiralix公司的主要服务包括:

Custom synthesis

Parallel synthesis of focused client-directed compound libraries

Route scouting

Disease state human plasma


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艾美捷科技代理Trialtusbioscience品牌全系列产品


TriAltus Bioscience是一个致力于为推动人类健康前沿的科学家服务的品牌。当今的创新者在推进基因疗法、工程诊断、早期疾病检测以及药物发现等领域,都需要高纯度、高性能且随时可以扩展的酶,TriAltus正是为此而存在。TriAltus的核心是其专有的CLiM™(CL7/Im7)纯化平台,是一种基于亲和标签的突破性系统,能在单个色谱步骤中提供具有卓越纯度、活性和一致性的酶,重新定义了重组蛋白纯化的可能性。 使用CLiM™生产的每种酶都以严格的质量控制、批次间一致性和详细的分析证书(COA)为后盾,旨在满足监管机构要求的质量和文档标准,支持从发现到扩大规模的更平稳过渡。TriAltus Bioscience公司的产品包括:基因组酶、蛋白酶和其他酶。


TriAltusBioscience页面.png


Trialtusbioscience产品线

● 基因组酶:TriAltus的重组基因组酶不含标签,并使用专有的CLiM™亲和标签系统进行纯化,提供目录酶的定制缩放和配方,以满足特定研究需求,无论需要更高的浓度、独特的缓冲条件还是批量生产,都可以根据具体规格定制酶。


货号品名规格产品描述
40-1212AapCas12b Protein20 μgexpressed in E. coli and features two C-terminal nuclear localization signals,enables the inactive nuclease to be guided to the specific double stranded DNA site.
40-1220AapCas12b Protein100 μg
40-1225AapCas12b Protein500 μg
40-1320CRISPR-Cas9 Protein100 μgused for genome editing with CRISPR technology. Recombinant Streptococcus pyogenes Cas9 ,expressed in Escherichia coli and features two nuclear localization signals
40-1325CRISPR-Cas9 Protein500 μg
40-2414Phi29 DNA Polymerase3,000 Unitsa highly processive, isothermal enzyme from Bacillus subtilis phage phi29 ,with a robust 3'→5' proofreading exonuclease function.
40-2420Phi29 DNA Polymerase10,000 Units
40-2125TAT-CRE Recombinase500 μgused for site-specific DNA recombination in mammalian cells,a fusion protein combining a nuclear localization sequence, HIV-TAT cell permeabilization peptide, and Cre recombinase.
40-2130TAT-CRE Recombinase1 mg
40-2135TAT-CRE Recombinase5 mg


● 蛋白酶和其他酶:例如为冷冻电镜生成蛋白质的实验室提供SUMO蛋白酶,去除相关标签后蛋白质可进行分析,反应高效、稳健,无需优化,客户对酶的性能和优质客户服务感到满意。


货号品名规格产品描述
30-2130PreScission Protease1 mgrecognizes and cleaves the sequence LEVLFQ/GP  to release the target protein from the Im7-bound CL7 tag
30-2135PreScission Protease5 mg
30-2140PreScission Protease10 mg
30-2146PreScission Protease50 mg
30-2150PreScission Protease100 mg
30-1130SUMO Protease1 mgreleases target proteins from TriAltus’s Im7 resin,recognizes SUMO tertiary structure – not a specific amino acid sequence – to cleave and release the target protein from the Im7-bound CL7 tag.
30-1135SUMO Protease5 mg
30-1140SUMO Protease10 mg
30-1146SUMO Protease50 mg
30-1150SUMO Protease100 mg



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